Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902816 | 0.92 | PDCD1 (0.41) | MAPTRXFP1SYKHSD17B10 | |
| SCHEMBL2909862 | 0.92 | GSK3B (0.38) | MAPTMAPK1TRPV1SYKALDH1A1 | |
| SCHEMBL2909504 | 0.84 | SYK (0.41) | SYKALDH1A1GAA | |
| SCHEMBL2908560 | 0.72 | L3MBTL1 (0.43) | L3MBTL1MAPK1ALDH1A1POLBLMNA | |
| SCHEMBL2908562 | 0.69 | ADORA2A (0.36) | MAPTFFAR2ALDH1A1GAAPOLB | |
| SCHEMBL2910476 | 0.69 | ADORA2A (0.36) | MAPTFFAR2ALDH1A1GAAPOLB | |
| SCHEMBL2910038 | 0.68 | SYK (0.39) | SYK | |
| SCHEMBL2906139 | 0.67 | KMT2A (0.41) | L3MBTL1ALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL2906140 | 0.63 | TP53 (0.35) | MAPTFFAR2ALDH1A1GAALMNA | |
| SCHEMBL2909267 | 0.63 | TP53 (0.35) | MAPTFFAR2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-B1 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARM CORP (US) | 2010-08-18 | — | — | EP | claimed |