Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098720 | 0.86 | MAPT (0.60) | MAPTTDP1PARP1ELANEALDH1A1 | |
| SCHEMBL31167604 | 0.85 | GPR52 (0.61) | MAPTGPR52HPGDTDP1PARP1 | |
| SCHEMBL7568121 | 0.84 | GPR52 (0.51) | MAPTGPR52HPGDPARP1ALDH1A1 | |
| SCHEMBL7171129 | 0.84 | GPR52 (0.51) | MAPTGPR52HPGDPARP1ALDH1A1 | |
| SCHEMBL9751109 | 0.83 | MAPT (0.72) | MAPTHPGDALDH1A1LMNAMDM2 | |
| SCHEMBL3371348 | 0.83 | MAPT (0.72) | MAPTHPGDALDH1A1LMNAMDM2 | |
| SCHEMBL3372572 | 0.83 | MAPT (0.72) | MAPTHPGDALDH1A1LMNAMDM2 | |
| SCHEMBL24951715 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1LMNA | |
| SCHEMBL28630576 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1LMNA | |
| SCHEMBL14601551 | 0.80 | ALDH1A1 (0.68) | MAPTGPR52HPGDTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554056-A | Cyclohexane compound with multiple functional groups and preparation method thereof | 贵州医科大学 | 2023-08-08 | — | — | CN | disclosed |