SCHEMBL2910068

SCHEMBL2910068

CCCCOC(=O)NC(CC(=O)O)SCc1ccc(OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
EPHX1 P07099 1/20 0.43
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
FAAH O00519 1/20 0.41
FFAR1 O14842 2/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
CTSK P43235 2/20 0.39
MAPK1 P28482 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909473 0.91 FAAH (0.41) CYP2C19SMN1; SMN2ALDH1A1EPHX1ATM
SCHEMBL2910217 0.82 TBXAS1 (0.42) SMN1; SMN2ALDH1A1FAAHCTSKMAPK1
SCHEMBL2910065 0.77 PPARA (0.64) PPARGPPARA
SCHEMBL2320404 0.77 FAAH (0.59) SMN1; SMN2ALDH1A1L3MBTL1FAAHMAPK1
SCHEMBL2909471 0.76 PPARA (0.53) FAAHCTSKPPARGPPARAGAA
SCHEMBL2320402 0.75 FPR2 (0.54)
SCHEMBL8485515 0.75 FPR2 (0.54)
SCHEMBL6623354 0.75 MAPT (0.44) ALDH1A1KDM4EGAA
SCHEMBL6692027 0.75 EPHX1 (0.41) SMN1; SMN2ALDH1A1EPHX1ATML3MBTL1
SCHEMBL6654292 0.73 FAAH (0.42) SMN1; SMN2POLBATML3MBTL1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220081-A2 GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT LG Life Sciences Ltd. (KR) 2010-08-25 EP disclosed
WO-2009082152-A2 GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT LG LIFE SCIENCES LTD. (KR) 2009-07-02 WO disclosed