Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909473 | 0.84 | FAAH (0.41) | MAPK1SMN1; SMN2GLAKMT2ACTSK | |
| SCHEMBL2910068 | 0.82 | CYP2C19 (0.47) | MAPK1SMN1; SMN2CTSKGAAKDM4E | |
| SCHEMBL7604900 | 0.78 | EPHX1 (0.45) | TBXAS1SMN1; SMN2GLAKMT2ALTA4H | |
| SCHEMBL2910214 | 0.74 | TAS1R3 (0.43) | MAPK1SMN1; SMN2GLAKMT2ATAS1R3 | |
| SCHEMBL2909471 | 0.72 | PPARA (0.53) | TAS1R3TAS1R1CTSKGAAFAAH | |
| SCHEMBL16334693 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2GLAKMT2AGAAALOX15 | |
| SCHEMBL2910065 | 0.71 | PPARA (0.64) | — | |
| SCHEMBL7999711 | 0.71 | ALOX5 (0.59) | GLAKMT2AMAPT | |
| SCHEMBL3675681 | 0.70 | ALOX5 (0.57) | GLAKMT2AMAPT | |
| SCHEMBL10641602 | 0.69 | GLA (0.45) | GLAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |