Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL8412858 | 0.95 | LMNA (0.53) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Methacrylic Acid SCHEMBL7941570 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRCA4TP53 | |
| Acrylic Acid SCHEMBL27914575 | 0.83 | LMNA (0.67) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Methacrylic Acid SCHEMBL29030326 | 0.83 | CA4 (0.53) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Methacrylic Acid SCHEMBL331575 | 0.83 | — | — | |
| Methacrylic Acid SCHEMBL1168962 | 0.81 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRCA4TP53 | |
| Methacrylic Acid SCHEMBL20954075 | 0.81 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRCA4TP53 | |
| Methacrylic Acid SCHEMBL20954078 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRCA4TP53 | |
| Methacrylic Acid SCHEMBL5712918 | 0.81 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRCA4TP53 | |
| Methacrylic Acid SCHEMBL9775691 | 0.81 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRCA4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108475761-B | Silicon-based materials and methods of making and using the same | 庄信万丰股份有限公司 | 2023-10-27 | — | — | CN | disclosed |