Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL7941570 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL20954078 | 0.94 | ALDH1A1 (0.47) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL20954075 | 0.94 | ALDH1A1 (0.45) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL1168962 | 0.94 | ALDH1A1 (0.45) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL5712918 | 0.94 | ALDH1A1 (0.45) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL5907607 | 0.92 | ALDH1A1 (0.45) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL7941579 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CA4TSHRTP53CA1 | |
| Pyruvate SCHEMBL7557962 | 0.86 | CA4 (0.59) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL11062591 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CA4TSHRTP53CA1 | |
| Methacrylic Acid SCHEMBL140446 | 0.85 | CA4 (0.53) | ALDH1A1CA4TSHRCA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511328-B | Branched-point-breaking type hyperbranched resin and preparation method and application thereof | 华南理工大学 | 2020-11-24 | — | — | CN | claimed |
| EP-4001345-B1 | DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF | UNIV SOUTH CHINA TECH (CN) | 2026-04-01 | — | — | EP | disclosed |
| EP-4001345-A1 | DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF | South China University of Technology (CN) | 2022-05-25 | — | — | EP | disclosed |
| CN-110511328-B | Branched-point-breaking type hyperbranched resin and preparation method and application thereof | 华南理工大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110540652-B | Degradable hyperbranched resin and preparation method and application thereof | 华南理工大学 | 2020-07-28 | — | — | CN | disclosed |
| CN-110540652-A | degradable hyperbranched resin and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2019-12-06 | — | — | CN | disclosed |
| US-4999279-A | Polyamide, Unsaturated Monomer, Metal (Meth)acrylate, N-Nitrosoamine Compound; Printed Plates | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0324485-A2 | Photosensitive resin composition | Toyo Boseki Kabushiki Kaisha (JP) | 1989-07-19 | — | — | EP | disclosed |