SCHEMBL29107151

SCHEMBL29107151

FC1(F)Oc2cc(Br)ccc2C1(F)F

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.40
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
BLM P54132 1/20 0.33
BACE1 P56817 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9875356 0.84 AHR (0.40) AHRLMNAMAPTHTTBLM
SCHEMBL316417 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL31085202 0.77 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL25116194 0.76
SCHEMBL21399749 0.76 MMP12 (0.33) MAPTHTT
SCHEMBL10687923 0.76 MAPT (0.38) MAPT
SCHEMBL3545157 0.70 AHR (0.31) AHR
SCHEMBL9349990 0.69 AHR (0.42) AHRLMNAMAPTHTTBLM
SCHEMBL12046 0.68 AHR (0.50) AHRLMNAMAPTHTTBLM
SCHEMBL31466520 0.67 LMNA (0.40) AHRLMNAMAPTHTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4298103-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS Enanta Pharmaceuticals, Inc. (US) 2024-01-03 EP disclosed
CN-117043166-A Antiviral heterocyclic compounds 英安塔制药有限公司 2023-11-10 CN disclosed
WO-2023200441-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARMACEUTICALS, INC. (US) 2023-10-19 WO disclosed
WO-2022182861-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARMACEUTICALS, INC. (US) 2022-09-01 WO disclosed