Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110964 | 0.83 | STAT3 (0.45) | HDAC8HDAC6KMT2AFFAR1LMNA | |
| SCHEMBL29110956 | 0.83 | HDAC8 (0.50) | HDAC8HDAC6KMT2AFFAR1MAPT | |
| SCHEMBL29110954 | 0.81 | HDAC8 (0.43) | HDAC8HDAC6FFAR1LMNAMAPT | |
| SCHEMBL1500385 | 0.81 | GABBR2 (0.48) | HDAC8HDAC6KMT2AFFAR1LMNA | |
| SCHEMBL29110970 | 0.79 | PTGS2 (0.49) | HDAC8HDAC6KMT2AFFAR1MAPT | |
| SCHEMBL13644278 | 0.79 | NR1I2 (0.49) | HDAC8HDAC6KMT2ALMNAMAPT | |
| SCHEMBL29110958 | 0.77 | CES2 (0.44) | HDAC8HDAC6FFAR1MAPT | |
| SCHEMBL12337676 | 0.76 | NR1I2 (0.57) | HDAC8HDAC6KMT2AL3MBTL1GAA | |
| SCHEMBL28983228 | 0.75 | KDM4E (0.46) | KMT2ALMNAMAPTPOLBHPGD | |
| SCHEMBL29110949 | 0.75 | L3MBTL1 (0.50) | FFAR1L3MBTL1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655459-A | Synthetic method for selectively synthesizing 4-aryl-2-hexanone | 河南大学 | 2023-08-29 | — | — | CN | disclosed |