SCHEMBL116765

SCHEMBL116765

CC1CCC(C(C)C)C(OCCCO)C1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
LMNA P02545 2/20 0.50
KDM4E B2RXH2 1/20 0.48
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
GAA P10253 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TRPA1 O75762 2/20 0.46
TRPM8 Q7Z2W7 2/20 0.46
P2RX4 Q99571 1/20 0.44
EPHX1 P07099 3/20 0.43
NTSR1 P30989 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HPGD P15428 1/20 0.43
CYP19A1 P11511 2/20 0.42
MAPT P10636 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15987982 1.00 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL943408 1.00 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL4582819 1.00 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1617541 0.95 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL3380568 0.95 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL30954762 0.95 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL291132 0.95 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14204903 0.94 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1616052 0.92 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL3388061 0.92 ALDH1A1 (0.67) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
EP-4471118-A1 PACKAGED CARBONATED ALCOHOLIC BEVERAGE CONTAINING GIN AND PRODUCTION METHOD THEREFOR Suntory Holdings Limited (JP) 2024-12-04 EP claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 US claimed
US-20240041726-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. 2024-02-08 US claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 US claimed
WO-2006127740-A2 INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
EP-1689256-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT Takasago International Corporation (JP) 2006-08-16 EP claimed
WO-2005115325-A1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-12-08 WO claimed
US-6956139-B2 (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-10-18 US claimed
WO-2005048743-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-02 WO claimed
US-6899901-B2 Sensate composition imparting initial sensation upon contact TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-05-31 US claimed
US-6838106-B2 Warming composition for food and drink or for oral care preparation TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-01-04 US claimed
US-20020198412-A1 (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate GREEN CARTER B (US) 2002-12-26 US claimed
US-20020142015-A1 Warming composition TAKASAGO INTERNATIONAL CORPORATION 2002-10-03 US claimed
EP-1215257-A2 Warming composition Takasago International Corporation (JP) 2002-06-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020142015-A1 Warming composition CUTA, TRPA1, POLR1C ALDH1A1 1699/4885LMNA 2473/4885KDM4E 3580/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 ALDH1A1 2893/4885LMNA 4817/4885KDM4E 4202/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 ALDH1A1 1658/4885LMNA 2062/4885KDM4E 3831/4885
US-20020198412-A1 (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate TAS1R1, TAS2R1, TAS1R3 ALDH1A1 76/4885LMNA 3297/4885KDM4E 2626/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALDH1A1 811/4885LMNA 3005/4885KDM4E 4049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.