Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683706 | 0.93 | LMNA (0.53) | PTPN1ACKR3DYRK1AALDH1A1AKR1B1 | |
| SCHEMBL29114941 | 0.93 | POLB (0.50) | PTPN1ACKR3ALDH1A1AKR1B1ALOX5 | |
| SCHEMBL29114917 | 0.93 | LMNA (0.53) | PTPN1ACKR3DYRK1AALDH1A1AKR1B1 | |
| SCHEMBL29114965 | 0.91 | DYRK1A (0.51) | PTPN1ACKR3DYRK1AFFAR1MAPT | |
| SCHEMBL29114964 | 0.84 | MAPT (0.53) | DYRK1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29114968 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL29114912 | 0.81 | CYP1A2 (0.58) | DYRK1AALDH1A1KMT2ALMNANPC1 | |
| SCHEMBL1413988 | 0.76 | DYRK1A (0.61) | DYRK1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6795234 | 0.75 | HTT (0.62) | PTPN1ACKR3ALDH1A1AKR1B1ALOX5 | |
| SCHEMBL15472020 | 0.75 | DYRK1A (0.59) | DYRK1AMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |