Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114956 | 0.93 | PTPN1 (0.53) | POLBACKR3AKR1B1PTPN1MAPT | |
| SCHEMBL30683706 | 0.90 | LMNA (0.53) | ACKR3AKR1B1PTPN1MAPTLMNA | |
| SCHEMBL29114917 | 0.90 | LMNA (0.53) | ACKR3AKR1B1PTPN1MAPTLMNA | |
| SCHEMBL29114965 | 0.84 | DYRK1A (0.51) | POLBACKR3GAAPTPN1MAPT | |
| SCHEMBL29114944 | 0.83 | ALDH1A1 (0.53) | MAPTLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL29114964 | 0.78 | MAPT (0.53) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL20181668 | 0.77 | AURKA (0.52) | TP53 | |
| SCHEMBL29115107 | 0.77 | KMT2A (0.56) | POLBGAAMAPTLMNAMEN1 | |
| SCHEMBL29114968 | 0.75 | SMN1; SMN2 (0.61) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL71738 | 0.74 | EGLN1 (0.51) | LMNAHTTTP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |