Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114956 | 0.81 | PTPN1 (0.53) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL29114965 | 0.81 | DYRK1A (0.51) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL29114964 | 0.79 | MAPT (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1040563 | 0.77 | ALDH1A1 (0.73) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL12443107 | 0.77 | ALDH1A1 (0.81) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29114917 | 0.75 | LMNA (0.53) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL29114941 | 0.75 | POLB (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30683706 | 0.75 | LMNA (0.53) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15306501 | 0.75 | KMT2A (1.00) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6940835 | 0.74 | ALDH1A1 (0.69) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |