Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677926 | 1.00 | MAP1LC3B (0.68) | MAP1LC3BNOD2ALDH1A1MAPTCYP2D6 | |
| SCHEMBL8580581 | 0.86 | MAP1LC3B (0.80) | MAP1LC3BALDH1A1MAPTCYP2D6MEN1 | |
| SCHEMBL29435850 | 0.83 | PLG (0.67) | MAP1LC3BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29115369 | 0.82 | MAP1LC3B (0.74) | MAP1LC3BALDH1A1MAPTCYP2D6MEN1 | |
| SCHEMBL30677928 | 0.82 | MAP1LC3B (0.74) | MAP1LC3BALDH1A1MAPTCYP2D6MEN1 | |
| SCHEMBL3787335 | 0.81 | MAP1LC3B (1.00) | MAP1LC3BALDH1A1MAPTCYP2D6MEN1 | |
| SCHEMBL29115413 | 0.80 | MAP1LC3B (0.76) | MAP1LC3BALDH1A1MAPTCYP2D6MEN1 | |
| SCHEMBL3783693 | 0.80 | ABCB1 (0.64) | MAP1LC3BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26804774 | 0.80 | NOD2 (1.00) | NOD2ALDH1A1MAPTCYP2D6MEN1 | |
| Acacetin SCHEMBL107712 | 0.78 | CYP1B1 (1.00) | ALDH1A1MAPTCYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143093-A | Protein degradation agent and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-12-01 | — | — | CN | disclosed |