Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.80 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.59 |
| ▸ | XDH | P47989 | 4/20 | 0.59 |
| ▸ | DAPK1 | P53355 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.59 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677928 | 0.89 | MAP1LC3B (0.74) | MAP1LC3BSIRT1ALDH1A1HPGDMAPT | |
| SCHEMBL29115369 | 0.89 | MAP1LC3B (0.74) | MAP1LC3BSIRT1ALDH1A1HPGDMAPT | |
| SCHEMBL3787335 | 0.89 | MAP1LC3B (1.00) | MAP1LC3BALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL29115413 | 0.88 | MAP1LC3B (0.76) | MAP1LC3BSIRT1ALDH1A1HPGDMAPT | |
| SCHEMBL29115331 | 0.86 | MAP1LC3B (0.68) | MAP1LC3BALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL30677926 | 0.86 | MAP1LC3B (0.68) | MAP1LC3BALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL3782904 | 0.84 | LMNA (0.67) | MAP1LC3BSIRT1ALDH1A1HPGDMAPT | |
| SCHEMBL5679746 | 0.79 | MAP1LC3B (0.73) | MAP1LC3BALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL536984 | 0.79 | ALDH1A1 (0.72) | MAP1LC3BALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL27442679 | 0.77 | CA12 (0.82) | ALDH1A1HPGDMAPTCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| WO-1998025608-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A 4-ARYLCOUMARIN FOR THE TREATMENT OF VIRAL INFECTIONS | BIO'S S.R.L. (IT) | 1998-06-18 | — | — | WO | disclosed |