Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115369 | 1.00 | MAP1LC3B (0.74) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL8580581 | 0.89 | MAP1LC3B (0.80) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL30231429 | 0.86 | MAP1LC3B (0.55) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL30228362 | 0.86 | ALDH1A1 (0.75) | MAP1LC3BALDH1A1TSHRALOX15MAPK1 | |
| SCHEMBL3787335 | 0.85 | MAP1LC3B (1.00) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL29115413 | 0.84 | MAP1LC3B (0.76) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL29115331 | 0.82 | MAP1LC3B (0.68) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL30677926 | 0.82 | MAP1LC3B (0.68) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL3782904 | 0.81 | LMNA (0.67) | MAP1LC3BABCB1ALDH1A1TSHRALOX15 | |
| SCHEMBL21648244 | 0.78 | CA12 (0.74) | ALDH1A1HPGDHSD17B10CA9CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143093-A | Protein degradation agent and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-12-01 | — | — | CN | disclosed |