Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536359 | 0.84 | IDO1 (0.56) | ALDH1A1PTGER1APP | |
| SCHEMBL11095203 | 0.82 | APP (0.47) | ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21462276 | 0.81 | L3MBTL1 (0.48) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 | |
| SCHEMBL488182 | 0.81 | RAB9A (0.58) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 | |
| SCHEMBL26128621 | 0.79 | DHFR (0.44) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 | |
| SCHEMBL487833 | 0.78 | JAK2 (0.58) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 | |
| SCHEMBL4812827 | 0.78 | APP (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19APP | |
| Hydrochloric Acid SCHEMBL4809393 | 0.77 | APP (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19APP | |
| SCHEMBL5921916 | 0.76 | RAB9A (0.56) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 | |
| SCHEMBL4638512 | 0.76 | MAOB (0.50) | ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730850-A | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |