Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118568 | 0.81 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL21465851 | 0.81 | MMP1 (0.41) | SLC6A4HTR2CPOLBLMNAMAPT | |
| SCHEMBL28569278 | 0.76 | RAB9A (0.47) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL6236728 | 0.76 | FABP4 (0.60) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL14774694 | 0.75 | PTGER1 (0.48) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL488182 | 0.75 | RAB9A (0.58) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL4162819 | 0.73 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3LMNAMAPT | |
| SCHEMBL26128621 | 0.73 | DHFR (0.44) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL487833 | 0.73 | JAK2 (0.58) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL4506944 | 0.73 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1ALOX15NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765482-A1 | NTCP INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019196953-A1 | NTCP INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2019-10-17 | — | — | WO | disclosed |