(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL29119950

C(=Cc1ccccc1)c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.67
TSHR P16473 1/20 0.67
TRPA1 O75762 1/20 0.56
TLR4 O00206 2/20 0.53
TLR2 O60603 2/20 0.53
MAOB P27338 2/20 0.52
PPARG P37231 1/20 0.52
RELA Q04206 2/20 0.50
MAOA P21397 2/20 0.50
CHEK1 O14757 1/20 0.50
FGFR1 P11362 1/20 0.50
KDR P35968 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CYP19A1 P11511 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
SRD5A2 P31213 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29098231 0.95 TRPA1 (0.64) LTA4HTSHRTRPA1TLR4TLR2
SCHEMBL20024694 0.92 LTA4H (0.63) LTA4HTSHRTRPA1TLR4TLR2
SCHEMBL1654499 0.92 TRPA1 (0.67) LTA4HTSHRTRPA1TLR4TLR2
SCHEMBL10031842 0.92 TRPA1 (0.67) LTA4HTSHRTRPA1TLR4TLR2
Diphenylether SCHEMBL847279 0.90 MAOB (0.70) LTA4HTSHRTRPA1TLR4TLR2
SCHEMBL2622615 0.85 MAOB (0.64) LTA4HTSHRTRPA1TLR4TLR2
Diphenylether SCHEMBL14776912 0.85 MAOB (0.64) LTA4HTSHRTRPA1TLR4TLR2
Diphenylether SCHEMBL4353122 0.84 MAOB (0.61) LTA4HTSHRTRPA1TLR4TLR2
SCHEMBL3079744 0.82 KMT2A (0.61) TRPA1TLR4TLR2MAOBPPARG
SCHEMBL19131747 0.82 ALDH1A1 (0.58) LTA4HTSHRTRPA1TLR4TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117203347-A Reagent composition and kit 电化株式会社 2023-12-08 CN disclosed