Diphenylether

Diphenylether

SCHEMBL847279

C(/C=C/c1ccccc1)=C\c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.70
LTA4H P09960 3/20 0.60
TSHR P16473 1/20 0.60
LMNA P02545 3/20 0.52
TRPA1 O75762 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 2/20 0.52
ALOX5 P09917 1/20 0.52
TLR4 O00206 2/20 0.50
TLR2 O60603 2/20 0.50
PPARG P37231 2/20 0.49
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SRD5A2 P31213 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL14776912 0.95 MAOB (0.64) MAOBLTA4HTSHRLMNATRPA1
SCHEMBL2622615 0.95 MAOB (0.64) MAOBLTA4HTSHRLMNATRPA1
Diphenylether SCHEMBL4353122 0.93 MAOB (0.61) MAOBLTA4HTSHRLMNATRPA1
(Z)-1,2-Diphenylethene SCHEMBL29119950 0.90 LTA4H (0.67) MAOBLTA4HTSHRTRPA1TLR4
Diphenylether SCHEMBL15412522 0.88 MAOB (0.54) MAOBLTA4HTSHRLMNATRPA1
SCHEMBL29098231 0.85 TRPA1 (0.64) MAOBLTA4HTSHRLMNATRPA1
SCHEMBL16273337 0.84 MAOB (0.50) MAOBLTA4HTSHRLMNATRPA1
SCHEMBL23458007 0.84 MAOB (1.00) MAOBLMNATRPA1ALDH1A1MAPK1
SCHEMBL592744 0.84 MAOB (1.00) MAOBLMNATRPA1ALDH1A1MAPK1
SCHEMBL5875512 0.84 MAOB (1.00) MAOBLMNATRPA1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3794944-B1 SAFENER NIPPON SODA CO (JP) 2023-10-18 EP disclosed
CN-112272518-B Chemical injury lightening agent 日本曹达株式会社 2022-06-07 CN disclosed
CN-110461616-B Receiving solution, ink set containing the receiving solution, and method for producing printed matter using the ink set DNP精细化工股份有限公司 2021-08-13 CN disclosed
US-20210227825-A1 SAFENER NIPPON SODA CO., LTD. (JP) 2021-07-29 US disclosed
EP-3794944-A1 PHYTOTOXICITY-REDUCING AGENT Nippon Soda Co., Ltd. (JP) 2021-03-24 EP disclosed
CN-112272518-A Chemical injury lightening agent 日本曹达株式会社 2021-01-26 CN disclosed
US-9901092-B2 Pest control agent in form of stable suspension NIPPON SODA CO., LTD. (JP) 2018-02-27 US disclosed
EP-2866556-B1 HERBICIDAL COMPOSITION HAVING IMPROVED HERBICIDAL ACTIVITY ISHIHARA SANGYO KAISHA (JP) 2017-10-11 EP disclosed
US-9526246-B2 Herbicidal composition having improved herbicidal activity ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-12-27 US disclosed
EP-2433987-B1 COMPOSITION FOR PREPARING EMULSION OR MICROEMULSION FORMULATIONS NIPPON SODA CO (JP) 2016-06-29 EP disclosed
US-20100234232-A1 EMULSION COMPOSITION AND AGROCHEMICAL EMULSION COMPOSITION NIPPON SODA CO., LTD. (JP) 2010-09-16 US disclosed
US-20100234436-A1 Pest control agent in form of stable suspension NIPPON SODA CO., LTD. (JP) 2010-09-16 US disclosed
EP-2216092-A1 EMULSION COMPOSITION AND AGROCHEMICAL EMULSION COMPOSITION Nippon Soda Co., Ltd. (JP) 2010-08-11 EP disclosed
US-6596292-B2 Mixture of dispersant, boron compound, smectite and water soluble carrier SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-22 US disclosed
EP-1166630-B1 Solid pesticidal formulation SUMITOMO CHEMICAL CO (JP) 2003-07-09 EP disclosed
US-20020019441-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-14 US disclosed
EP-1166630-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed
EP-0179458-B1 ROSIN EMULSION SIZING AGENT DIC-HERCULES CHEMICALS, INC. (JP) 1989-01-25 EP disclosed
US-4681909-A SAPONIFIED STYRENE-(METH)ACRYLIC ACID COPOLYMER DIC-HERCULES CHEMICALS, INC. (JP) 1987-07-21 US disclosed
EP-0179458-A1 Rosin emulsion sizing agent DIC-HERCULES CHEMICALS, INC. (JP) 1986-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210227825-A1 SAFENER CYP2W1, CYP4Z1, WEE1 MAOB 2691/4885LTA4H 4439/4885TSHR 3523/4885
US-20100234232-A1 EMULSION COMPOSITION AND AGROCHEMICAL EMULSION COMPOSITION ALK, AHR, PHOSPHO1 MAOB 2613/4885LTA4H 1269/4885TSHR 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.