Diphenylether

Diphenylether

SCHEMBL4353122

C(/C=C/c1ccccc1)=C\c1ccccc1.C=O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.61
LTA4H P09960 1/20 0.52
TSHR P16473 1/20 0.52
LMNA P02545 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TRPA1 O75762 2/20 0.52
ALOX5 P09917 2/20 0.52
MAPK1 P28482 1/20 0.52
TLR4 O00206 2/20 0.50
TLR2 O60603 2/20 0.50
PPARG P37231 2/20 0.49
SRD5A2 P31213 1/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL14776912 0.93 MAOB (0.64) MAOBLTA4HTSHRLMNAALDH1A1
Diphenylether SCHEMBL847279 0.93 MAOB (0.70) MAOBLTA4HTSHRLMNAALDH1A1
SCHEMBL2622615 0.89 MAOB (0.64) MAOBLTA4HTSHRLMNAALDH1A1
Diphenylether SCHEMBL15412522 0.86 MAOB (0.54) MAOBLTA4HTSHRLMNAALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL29119950 0.84 LTA4H (0.67) MAOBLTA4HTSHRTRPA1TLR4
Diphenylether SCHEMBL22204373 0.81 LTA4H (0.80) MAOBLTA4HTSHRSRD5A2PARP10
Diphenylether SCHEMBL1566663 0.81 LTA4H (0.80) MAOBLTA4HTSHRSRD5A2PARP10
SCHEMBL29098231 0.79 TRPA1 (0.64) MAOBLTA4HTSHRLMNAALDH1A1
SCHEMBL7184284 0.79 ALDH1A1 (0.65) MAOBLTA4HTSHRLMNAALDH1A1
SCHEMBL10849454 0.79 ALDH1A1 (0.65) MAOBLTA4HTSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273685-B2 Agrochemical composition NIPPON SODA CO., LTD. (JP) 2012-09-25 US disclosed
US-20090286682-A1 AGROCHEMICAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286682-A1 AGROCHEMICAL COMPOSITION DEGS1, PFAS, SGMS1 MAOB 2924/4885LTA4H 2887/4885TSHR 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.