Succinylacetone

Succinylacetone

SCHEMBL29120445

CC(=O)CC(=O)CCC(=O)O.CC[Al](CC)CC

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 6/20 0.75
KDM2A Q9Y2K7 6/20 0.75
EGLN1 Q9GZT9 4/20 0.75
KDM4E B2RXH2 3/20 0.75
KDM5C P41229 3/20 0.75
KDM6B O15054 2/20 0.75
LMNA P02545 2/20 0.52
SLC15A2 Q16348 1/20 0.52
GABRR1 P24046 1/20 0.43
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
ACE P12821 1/20 0.37
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 2/20 0.33
FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinylacetone SCHEMBL503918 0.87 PHF8 (1.00) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL9839290 0.82 PHF8 (0.90) PHF8KDM2AEGLN1KDM4EKDM5C
Acetoacetic Acid SCHEMBL28137247 0.80 LMNA (0.43) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL7016070 0.77 KDM4E (0.70) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL61062 0.76 KDM4E (0.78) PHF8KDM2AEGLN1KDM4EKDM5C
Water SCHEMBL28556088 0.74 ALDH1A1 (0.42) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL28505622 0.74 LMNA (0.82) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL21174517 0.74 LMNA (0.82) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL26625806 0.74 LMNA (0.82) PHF8KDM2AEGLN1KDM4EKDM5C
Butyric Acid SCHEMBL27933814 0.74 PHF8 (0.67) PHF8KDM2AEGLN1KDM4EKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113881280-B Mixed LED-UV rotary ink, preparation method thereof and LED-UV curing rotary printing machine 杭华油墨股份有限公司 2023-12-12 CN disclosed