⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636667 | 0.85 | GABRA1 (0.37) | — | |
| SCHEMBL7701042 | 0.74 | — | — | |
| SCHEMBL11731891 | 0.74 | — | — | |
| SCHEMBL10531181 | 0.74 | — | — | |
| SCHEMBL10514297 | 0.73 | TDP1 (0.34) | — | |
| SCHEMBL3557423 | 0.71 | — | — | |
| SCHEMBL7703138 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL1443362 | 0.70 | CA2 (0.35) | — | |
| SCHEMBL6205052 | 0.69 | TDP1 (0.42) | — | |
| SCHEMBL7934802 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884010-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| EP-2219668-A1 | BINDING EPITOPES FOR G250 ANTIBODY | Wilex AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009056342-A1 | BINDING EPITOPES FOR G250 ANTIBODY | WILEX AG (DE) | 2009-05-07 | — | — | WO | disclosed |