Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123788 | 0.91 | IDH1 (0.37) | LTA4HPPARDPPARASCN9AP2RX3 | |
| SCHEMBL29123581 | 0.88 | SCN9A (0.44) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL30731710 | 0.82 | LTA4H (0.44) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL29123425 | 0.82 | LTA4H (0.44) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL29123660 | 0.79 | SCN9A (0.37) | LTA4HSCN9AP2RX3 | |
| SCHEMBL29123777 | 0.79 | LTA4H (0.51) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL29123780 | 0.79 | LTA4H (0.51) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL30731591 | 0.76 | PPARD (0.43) | LTA4HACACBPPARDPPARASCN9A | |
| SCHEMBL29123787 | 0.74 | MAPT (0.38) | LTA4HSCN9A | |
| SCHEMBL27171420 | 0.72 | LTA4H (0.68) | LTA4HACACBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |