Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123581 | 0.90 | SCN9A (0.44) | SCN9AFPR2LTA4HMAPTFFAR1 | |
| SCHEMBL29123788 | 0.88 | IDH1 (0.37) | SCN9AS1PR1LTA4HMAPTP2RX3 | |
| SCHEMBL29123657 | 0.82 | SCN9A (0.39) | SCN9AFPR2PPARGLTA4HMAPT | |
| SCHEMBL30731741 | 0.82 | SCN9A (0.39) | SCN9AFPR2PPARGLTA4HMAPT | |
| SCHEMBL29123584 | 0.79 | LTA4H (0.43) | SCN9AFPR2PPARGLTA4HMAPT | |
| SCHEMBL29123582 | 0.79 | LTA4H (0.43) | SCN9AFPR2PPARGLTA4HMAPT | |
| SCHEMBL29123428 | 0.79 | LTA4H (0.40) | SCN9ALTA4HP2RX3 | |
| SCHEMBL24665357 | 0.73 | LTA4H (0.58) | LTA4HNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27204649 | 0.73 | LTA4H (0.58) | LTA4HNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24665367 | 0.72 | LTA4H (0.38) | PPARGLTA4HMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |