Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195100 | 0.80 | RAB9A (0.59) | HCAR2RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL9195173 | 0.80 | HCAR2 (0.45) | HCAR2HTTRAB9AMAPTNPC1 | |
| SCHEMBL3817859 | 0.78 | TNKS2 (0.44) | HCAR2ALDH1A1TP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL6440045 | 0.77 | HCAR2 (0.43) | HCAR2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL9190029 | 0.77 | ALDH1A1 (0.43) | HCAR2PDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL9191469 | 0.76 | HCAR2 (0.47) | HCAR2PDE9APDE1APDE1BPDE1C | |
| SCHEMBL9195013 | 0.76 | HCAR2 (0.37) | HCAR2PDE9APDE1APDE1BPDE1C | |
| SCHEMBL9189988 | 0.75 | HCAR2 (0.56) | HCAR2RAB9A | |
| SCHEMBL9196970 | 0.75 | RAB9A (0.49) | HCAR2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL9191276 | 0.75 | HCAR2 (0.51) | HCAR2ALDH1A1HTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |