Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128275 | 0.88 | SOD1 (0.33) | SOD1LMNAPOLBHTTL3MBTL1 | |
| SCHEMBL29128175 | 0.87 | METAP2 (0.30) | — | |
| SCHEMBL29125938 | 0.82 | SOD1 (0.36) | SOD1LMNAPOLBHTTL3MBTL1 | |
| SCHEMBL29128379 | 0.74 | MAOA (0.31) | — | |
| SCHEMBL29128416 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL29125717 | 0.74 | ALDH1A1 (0.47) | LMNAPOLBHTTL3MBTL1CYP3A4 | |
| SCHEMBL29128371 | 0.73 | LMNA (0.36) | LMNAPOLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29128405 | 0.73 | PPARG (0.38) | LMNACYP3A4CYP2C9CYP2C19PPARG | |
| SCHEMBL29128305 | 0.70 | — | — | |
| SCHEMBL29128487 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |