Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128364 | 0.86 | LMNA (0.34) | LMNASMN1; SMN2ATMMAPK1TSHR | |
| SCHEMBL29128493 | 0.82 | SOD1 (0.36) | LMNAHPGDALDH1A1 | |
| SCHEMBL29128360 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL29125950 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2ATMHPGDNPC1 | |
| SCHEMBL29128255 | 0.78 | POLB (0.34) | TDP1L3MBTL1 | |
| SCHEMBL29128588 | 0.77 | MAPT (0.37) | SMN1; SMN2HPGDRAB9AALDH1A1TDP1 | |
| SCHEMBL29128294 | 0.76 | POLB (0.31) | — | |
| SCHEMBL29128548 | 0.76 | L3MBTL1 (0.34) | TSHRALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29128435 | 0.75 | POLB (0.35) | TSHRTDP1L3MBTL1MAPT | |
| SCHEMBL29128519 | 0.74 | ADRA2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |