Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128255 | 0.87 | POLB (0.34) | TDP1USP2PABPC1L3MBTL1POLB | |
| SCHEMBL29128323 | 0.86 | ALDH1A1 (0.31) | ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL29128435 | 0.84 | POLB (0.35) | MAPTTDP1USP2PABPC1L3MBTL1 | |
| SCHEMBL29128548 | 0.83 | L3MBTL1 (0.34) | ALDH1A1TDP1USP2PABPC1L3MBTL1 | |
| SCHEMBL29128294 | 0.82 | POLB (0.31) | POLB | |
| SCHEMBL29128531 | 0.78 | TACR1 (0.32) | MAPTALDH1A1DAOSMN1; SMN2MEN1 | |
| SCHEMBL29128519 | 0.78 | ADRA2A (0.34) | DAOADRA2AADRA2BADRA2C | |
| SCHEMBL29128360 | 0.78 | LMNA (0.32) | DAO | |
| SCHEMBL29128522 | 0.77 | LMNA (0.36) | MAPTALDH1A1TDP1L3MBTL1HPGD | |
| SCHEMBL29128516 | 0.76 | MAPT (0.35) | MAPTALDH1A1DAOHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |