Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253203 | 0.87 | ALDH1A1 (0.47) | KMT2AMMP2ADAM17MMP13MMP1 | |
| SCHEMBL9218545 | 0.85 | POLB (0.47) | KMT2AESRRBMMP13POLB | |
| SCHEMBL8414713 | 0.85 | POLB (0.47) | KMT2AESRRBMMP13POLB | |
| SCHEMBL2923150 | 0.77 | CA2 (0.52) | KMT2AMMP2MMP13MMP1ESR1 | |
| SCHEMBL7697681 | 0.74 | MMP13 (0.56) | KMT2AMMP2ADAM17MMP13MMP1 | |
| SCHEMBL23370067 | 0.73 | AOC2 (0.53) | KMT2AMMP2MMP13MMP1ESR1 | |
| SCHEMBL4185343 | 0.73 | ESR1 (0.65) | KMT2AESRRBESR1ESR2CA2 | |
| SCHEMBL5546946 | 0.73 | ESR1 (0.65) | KMT2AESRRBESR1ESR2CA2 | |
| SCHEMBL15314148 | 0.73 | ESR1 (0.65) | KMT2AESRRBESR1ESR2CA2 | |
| SCHEMBL2586496 | 0.72 | CA12 (0.53) | KMT2ACA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997546-A | APOL1 inhibitors and methods of use | 梅兹治疗公司 | 2023-11-03 | — | — | CN | disclosed |