Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425661 | 0.85 | SIGMAR1 (0.35) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL25423853 | 0.81 | MAPK1 (0.37) | MAPK1GPR119KDM1AUSP30NR1H2 | |
| SCHEMBL30151394 | 0.75 | NR1H2 (0.40) | MAPK1GPR119KDM1AUSP30NR1H2 | |
| SCHEMBL28637688 | 0.75 | NR1H2 (0.40) | MAPK1GPR119KDM1ANR1H2NR1H3 | |
| SCHEMBL3733138 | 0.74 | MAPK1 (0.39) | MAPK1GPR119KDM1AUSP30NR1H2 | |
| SCHEMBL4321471 | 0.74 | STS (0.39) | MAPK1GPR119KDM4EPKMTACR1 | |
| SCHEMBL28029544 | 0.73 | MAPK1 (0.39) | MAPK1GPR119KDM1AUSP30NR1H2 | |
| SCHEMBL4710880 | 0.73 | NR1H2 (0.39) | MAPK1GPR119NR1H2NR1H3KDM4E | |
| SCHEMBL27848384 | 0.73 | GPR119 (0.42) | MAPK1GPR119KDM1AUSP30NR1H2 | |
| SCHEMBL27848285 | 0.73 | KDM4E (0.41) | MAPK1GPR119KDM1AUSP30NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279636-A | Methods and compounds for modulating myotonic muscular dystrophy type 1 | 设计治疗公司 | 2023-12-22 | — | — | CN | disclosed |