SCHEMBL29129796

SCHEMBL29129796

Nc1ccc(-c2c(CO)c(CO)c(N)c(CO)c2CO)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 1/20 0.42
HSD17B10 Q99714 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
APP P05067 2/20 0.33
CA3 P07451 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
CA6 P23280 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GCGR P47871 3/20 0.33
ACHE P22303 1/20 0.32
GFER P55789 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596717 0.74 TDP1 (0.42) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL379634 0.72 CYP3A4 (0.41) CYP3A4TDP1ALDH1A1TP53HSD17B10
Methane SCHEMBL28192521 0.72 TDP1 (0.40) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL6020612 0.70 CYP3A4 (0.62) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL5333327 0.69 ALDH1A1 (0.37) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL29450595 0.69 CYP3A4 (0.71) CYP3A4TDP1ALDH1A1TP53HSD17B10
Hydrochloric Acid SCHEMBL10885436 0.68 ALDH1A1 (0.36) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL2331006 0.68 GCGR (0.38) CYP3A4TDP1ALDH1A1TP53HSD17B10
SCHEMBL2407662 0.68 MAOB (0.45) CYP3A4TDP1ALDH1A1HSD17B10TAAR1
SCHEMBL9330651 0.68 CYP3A4 (0.59) CYP3A4TDP1ALDH1A1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112213491-B Kit for rapidly detecting drugs in hair and application of kit 自然资源部第三海洋研究所 2024-04-12 CN disclosed
CN-117070795-A Preparation method of magnetic amorphous metal nano material 陕西中医药大学 2023-11-17 CN disclosed