Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037137 | 0.88 | IDO1 (0.47) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL8746636 | 0.83 | AKR1B1 (0.46) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL2243225 | 0.83 | TDP1 (0.49) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7445814 | 0.79 | ALOX5 (0.53) | MEN1KMT2AAKR1B1CYP1A2 | |
| SCHEMBL819647 | 0.79 | TDP1 (0.68) | MEN1KMT2AKDM4ETDP1MAPT | |
| SCHEMBL29131708 | 0.79 | TDP1 (0.61) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3423124 | 0.78 | TDP1 (0.43) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3423716 | 0.78 | TDP1 (0.44) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3422965 | 0.78 | TDP1 (0.46) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL11467086 | 0.78 | AKR1B1 (0.42) | MEN1KMT2AALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0644232-A1 | Free radical cured rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-03-22 | — | — | EP | claimed |
| US-5310811-A | Abrasion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| US-8080603-B2 | Low hysteresis rubber elastomer | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2011-12-20 | — | — | US | disclosed |
| US-20100056686-A1 | LOW HYSTERESIS RUBBER ELASTOMER | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2010-03-04 | — | — | US | disclosed |
| US-20100012241-A1 | CUSHION GUM | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-2114696-A1 | LOW HYSTERESIS RUBBER ELASTOMER | Societe de Technologie Michelin (FR) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008079726-A1 | CUSHION GUM | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008079107-A1 | LOW HYSTERESIS RUBBER ELASTOMER | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2008-07-03 | — | — | WO | disclosed |
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0644232-A1 | Free radical cured rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5310811-A | Abrasion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | disclosed |