Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042822 | 0.81 | VCAM1 (0.50) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL28498687 | 0.79 | FSCN1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28492096 | 0.78 | HTT (0.33) | HTTMAPT | |
| SCHEMBL28490898 | 0.78 | FSCN1 (0.49) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL28501470 | 0.78 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL28497420 | 0.75 | MAPT (0.41) | ALDH1A1HTTLMNAL3MBTL1MAPK1 | |
| SCHEMBL1026260 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL1026262 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL28499201 | 0.74 | GAA (0.35) | ALDH1A1TP53GAASMN1; SMN2 | |
| SCHEMBL28499158 | 0.73 | GAA (0.36) | ALDH1A1TP53MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | claimed |
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | disclosed |