SCHEMBL29132352

SCHEMBL29132352

Cc1cc(C)nc(C)c1.Cc1cccc(B(O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 5/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
NPC1 O15118 1/20 0.42
GBA1 P04062 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MGLL Q99685 2/20 0.41
ACHE P22303 3/20 0.39
CA2 P00918 2/20 0.39
LPL P06858 2/20 0.39
LIPG Q9Y5X9 2/20 0.39
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398358 0.86 ENPP2 (0.56) ENPP2KDM4EALDH1A1MGLLACHE
SCHEMBL102540 0.86 ENPP2 (0.56) ENPP2KDM4EALDH1A1MGLLACHE
Dimethylamine SCHEMBL3761544 0.80 ENPP2 (0.50) ENPP2KDM4EALDH1A1MGLLACHE
Tolyl Boronic Acid SCHEMBL29132351 0.79 CA2 (0.67) ENPP2CA2LPLLIPGCA1
Sulfamide SCHEMBL2319598 0.76 ENPP2 (0.48) ENPP2KDM4EALDH1A1MGLLACHE
Boric Acid SCHEMBL31442978 0.75 NOS3 (0.52) KDM4EALDH1A1NPC1GBA1MAPK1
SCHEMBL17899782 0.75 MGLL (0.67) ENPP2KDM4EALDH1A1MGLLACHE
SCHEMBL7183051 0.73 ACHE (0.52) ENPP2KDM4EALDH1A1MAPK1ACHE
SCHEMBL3132606 0.73 ENPP2 (0.56) ENPP2KDM4EALDH1A1MGLLACHE
SCHEMBL590848 0.73 CA2 (0.42) ENPP2CA2LPLLIPGCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116973436-A Mass spectrum imaging detection method for compound containing ortho-diphenol hydroxyl functional group in tissue 中国科学院大连化学物理研究所 2023-10-31 CN disclosed