Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132913 | 0.91 | PLA2G4A (0.43) | CNR1PLA2G4AAKR1B1L3MBTL1KDM5A | |
| SCHEMBL22291138 | 0.83 | CNR1 (0.56) | CNR1PLA2G4AALDH1A1PLA2G4BRARB | |
| SCHEMBL21413172 | 0.83 | CNR1 (0.56) | CNR1PLA2G4AALDH1A1PLA2G4BRARB | |
| SCHEMBL9150323 | 0.83 | CNR1 (0.56) | CNR1PLA2G4AALDH1A1PLA2G4BRARB | |
| SCHEMBL7755595 | 0.82 | KDM5A (0.48) | CNR1PLA2G4AAKR1B1L3MBTL1KDM5A | |
| SCHEMBL3261973 | 0.76 | AKR1B1 (0.41) | CNR1PLA2G4AAKR1B1TBXAS1 | |
| SCHEMBL22748618 | 0.75 | PLA2G4A (0.50) | CNR1PLA2G4APLA2G4BRARB | |
| SCHEMBL26134331 | 0.75 | AKR1B1 (0.43) | CNR1PLA2G4AAKR1B1L3MBTL1TBXAS1 | |
| SCHEMBL969727 | 0.75 | AKR1B1 (0.46) | CNR1PLA2G4AAKR1B1L3MBTL1KDM5A | |
| SCHEMBL22748727 | 0.73 | CNR1 (0.40) | CNR1PLA2G4AAKR1B1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-112118845-B | MCL-1 inhibitors | 吉利德科学公司 | 2023-06-13 | — | — | CN | disclosed |