Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132872 | 0.91 | CNR1 (0.46) | PLA2G4ACNR1L3MBTL1AKR1B1KDM5A | |
| SCHEMBL7755595 | 0.84 | KDM5A (0.48) | PLA2G4ACNR1L3MBTL1AKR1B1KDM5A | |
| SCHEMBL22291138 | 0.79 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1SMN1; SMN2PLA2G4B | |
| SCHEMBL21413172 | 0.79 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1SMN1; SMN2PLA2G4B | |
| SCHEMBL9150323 | 0.79 | CNR1 (0.56) | PLA2G4ACNR1ALDH1A1SMN1; SMN2PLA2G4B | |
| SCHEMBL26134331 | 0.78 | AKR1B1 (0.43) | PLA2G4ACNR1L3MBTL1AKR1B1ALDH1A1 | |
| SCHEMBL969727 | 0.77 | AKR1B1 (0.46) | PLA2G4ACNR1L3MBTL1AKR1B1KDM5A | |
| SCHEMBL22063999 | 0.73 | ALDH1A1 (0.47) | PLA2G4AAKR1B1ALDH1A1HCAR3 | |
| SCHEMBL22748618 | 0.72 | PLA2G4A (0.50) | PLA2G4ACNR1PLA2G4B | |
| SCHEMBL22749024 | 0.72 | PLA2G4A (0.47) | PLA2G4ACNR1ALDH1A1CES2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |