Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132876 | 0.85 | HCAR3 (0.38) | HCAR3ALDH1A1HTTMAPTKDM4C | |
| SCHEMBL15559838 | 0.72 | TSHR (0.39) | HCAR3ALDH1A1MAPTHCAR2MEN1 | |
| SCHEMBL24035819 | 0.69 | HCAR3 (0.35) | HCAR3ALDH1A1MAPTKDM4CACHE | |
| SCHEMBL18696360 | 0.69 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL22748596 | 0.67 | ALDH1A1 (0.41) | ALDH1A1MAPTPLA2G4AMEN1KMT2A | |
| SCHEMBL24853072 | 0.67 | HCAR3 (0.46) | HCAR3ALDH1A1HTTMAPTLPAR1 | |
| SCHEMBL969727 | 0.65 | AKR1B1 (0.46) | HCAR3ALDH1A1MAPTL3MBTL1PLA2G4A | |
| SCHEMBL7089141 | 0.64 | PGR (0.34) | ALDH1A1 | |
| SCHEMBL22290905 | 0.63 | TSHR (0.40) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7755595 | 0.62 | KDM5A (0.48) | HCAR3ALDH1A1L3MBTL1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |