Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442248 | 0.76 | PDE4A (0.54) | HDAC1HDAC6LTA4HLMNAMEN1 | |
| SCHEMBL5493573 | 0.74 | HDAC6 (0.50) | HDAC1HDAC6LTA4HLMNAMEN1 | |
| 9-Benzyl-9H-Purine SCHEMBL434620 | 0.73 | HDAC1 (0.61) | HDAC1HDAC6LTA4HMAPK1LMNA | |
| SCHEMBL28950085 | 0.70 | HDAC1 (0.44) | HDAC1HDAC6LTA4HLMNAMEN1 | |
| SCHEMBL28950112 | 0.69 | LTA4H (0.47) | HDAC1HDAC6LTA4HMAPK1LMNA | |
| SCHEMBL9809679 | 0.66 | GRK2 (0.51) | HPGDL3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL29133991 | 0.66 | HPGD (0.80) | HDAC1HPGDL3MBTL1MAPK1MAPT | |
| SCHEMBL6946794 | 0.66 | LTA4H (0.64) | HDAC1HDAC6LTA4HMAPK1LMNA | |
| SCHEMBL10602614 | 0.66 | FDPS (0.56) | HDAC1HDAC6LTA4HMAPK1LMNA | |
| SCHEMBL6941744 | 0.64 | STAT3 (0.52) | HDAC1HDAC6LTA4HHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117107254-A | Method for synthesizing tricyclo [1,2,4] triazole- [3,4-i ] purine nucleoside compound | 河南师范大学 | 2023-11-24 | — | — | CN | disclosed |