9-Benzyl-9H-Purine

9-Benzyl-9H-Purine

SCHEMBL434620

c1ccc(Cn2cnc3cncnc32)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
LTA4H P09960 1/20 0.60
CYP1A2 P05177 4/20 0.58
CYP2C9 P11712 4/20 0.58
CYP2C19 P33261 4/20 0.58
LMNA P02545 3/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 3/20 0.58
MEN1 O00255 1/20 0.58
TSHR P16473 1/20 0.58
HBB P68871 1/20 0.58
KMT2A Q03164 1/20 0.58
TNF P01375 1/20 0.54
CYP11B1 P15538 1/20 0.54
CYP11B2 P19099 1/20 0.54
ADORA2A P29274 1/20 0.54
PI4KA P42356 1/20 0.54
PI4K2B Q8TCG2 1/20 0.54
PI4K2A Q9BTU6 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
9-Benzyl-9H-Purine SCHEMBL30586391 0.84 CYP11B1 (0.51) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL6944736 0.84 HDAC1 (0.62) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL6946794 0.84 LTA4H (0.64) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL28195658 0.81 HDAC1 (0.58) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL6946826 0.81 HDAC6 (0.62) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL28950112 0.79 LTA4H (0.47) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL10442248 0.79 PDE4A (0.54) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL5493573 0.79 HDAC6 (0.50) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL28038025 0.79 LTA4H (0.58) HDAC1HDAC6LTA4HCYP1A2CYP2C9
SCHEMBL10602614 0.78 FDPS (0.56) HDAC1HDAC6LTA4HCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118805676-A Rapid training method for bird's nest fruits 海南希源生态农业股份有限公司 2024-10-22 CN claimed
CN-117099578-A Nutritional propagation method of onion male sterile plant 兰州龙腾农业科技有限公司 2023-11-24 CN claimed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 EP claimed
CN-113998653-A Culture medium subpackaging device and preparation method thereof 广西壮族自治区农业科学院 2022-02-01 CN claimed
US-11133468-B2 Semiconductor nanocrystal-ligand composite and device including composite SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-09-28 US claimed
CN-112913690-A Peony in-vitro regeneration method 四川农业大学 2021-06-08 CN claimed
US-10202411-B2 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV IDENIX PHARMACEUTICALS LLC (US) 2019-02-12 US claimed
CN-109197582-A A kind of culture medium of golden flower tea callus bud induction 罗甸县五湖生态农业旅游开发有限责任公司 2019-01-15 CN claimed
CN-108935094-A A kind of bletilla striata cultural method rapidly and efficiently 贵州发来地农业科技有限公司 2018-12-07 CN claimed
CN-108935093-A A kind of bletilla striata tissue culture method primary 贵州发来地农业科技有限公司 2018-12-07 CN claimed
US-20040087806-A1 Processes for preparing 1,3-dioxolane nucleosides PHARMASSET, INC. 2004-05-06 US claimed
WO-2004028445-A2 PROCESSES FOR PREPARING 1,3-DIOXOLANE NUCLEOSIDES PHARMASSET INC. (US) 2004-04-08 WO claimed
CN-1453251-A Acid liquid fertilizer for drip irrigation and its prepn INST PROCESS ENG CAS (CN) 2003-11-05 CN claimed
US-6518425-B1 A process for producing a 1,3-oxathiolane nucleoside comprising reacting a 5-halo-2-protected-oxymethyl-1,3-oxathiolane with a silylated purine or pyrimidine without the addition of a Lewis acid or an additional base to the reaction EMORY UNIVERSITY 2003-02-11 US claimed
US-20030013880-A1 Process for recovery of the desired cis-1,3-oxathiolane nucleosides from their undesired trans-isomers APOTEX PHARMACHEM INC (CA) 2003-01-16 US claimed
CN-1085042-A Biocide for protecting cotton bolls and eliminating fusarium wilt of cotton WANG LIANFANG (CN) 1994-04-13 CN claimed
EP-0562009-A4 ENANTIOMERICALLY PURE -G(B)-D-(-)-DIOXOLANE-NUCLEOSIDES 1993-11-24 EP claimed
EP-0562009-A1 ENANTIOMERICALLY PURE $g(b)-D-(-)-DIOXOLANE-NUCLEOSIDES THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-09-29 EP claimed
WO-1992010496-A1 ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO claimed
WO-1992010497-A1 ENANTIOMERICALLY PURE β-D-(-)-DIOXOLANE-NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087806-A1 Processes for preparing 1,3-dioxolane nucleosides NUDT1, PNP, DPYD HDAC1 4387/4885HDAC6 4717/4885LTA4H 2723/4885
US-20030013880-A1 Process for recovery of the desired cis-1,3-oxathiolane nucleosides from their undesired trans-isomers SLC29A1, NUDT1, SLC28A1 HDAC1 2911/4885HDAC6 3283/4885LTA4H 3373/4885
US-10202411-B2 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV RB1, NSUN2, METTL3 HDAC1 3021/4885HDAC6 2467/4885LTA4H 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.