Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984281 | 0.88 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| SCHEMBL5137806 | 0.87 | MAPT (0.87) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| Prudomestin SCHEMBL30977124 | 0.85 | ABCB1 (0.65) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| 5-Hydroxyauranetin SCHEMBL4066374 | 0.85 | MAPT (0.71) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| SCHEMBL30049379 | 0.85 | MAPT (0.62) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| SCHEMBL30050183 | 0.84 | MAPT (0.65) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| SCHEMBL16894648 | 0.84 | ABCG2 (0.66) | ALDH1A1KDM4EMAPTGAAABCG2 | |
| Tambulin SCHEMBL4742083 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTABCG2ABCB1MAOA | |
| Tambulin SCHEMBL29728591 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTABCG2ABCB1MAOA | |
| Natsudaidai SCHEMBL890712 | 0.83 | ABCG2 (0.79) | ALDH1A1KDM4EMAPTGAAABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | claimed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | claimed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | disclosed |
| CN-112830917-A | Hydroxylated polymethoxyflavone and preparation method thereof | 五邑大学 | 2021-05-25 | — | — | CN | disclosed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | disclosed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | disclosed |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | WELLGEN, INC. | 2007-04-19 | — | — | US | disclosed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | disclosed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | ALDH1A1 3163/4885KDM4E 121/4885MAPT 4515/4885 |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | FABP4, PLIN5, PLIN3 | ALDH1A1 1272/4885KDM4E 248/4885MAPT 3872/4885 |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | ALDH1A1 1794/4885KDM4E 1277/4885MAPT 4329/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | ALDH1A1 1794/4885KDM4E 1277/4885MAPT 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.