Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956756 | 0.74 | PRKAB2 (0.43) | MEN1NPC1KMT2AKDM4EPOLB | |
| SCHEMBL30014820 | 0.74 | KDM4E (0.37) | MEN1NPC1KMT2AKDM4EPOLB | |
| SCHEMBL29134375 | 0.74 | KDM4E (0.37) | MEN1NPC1KMT2AKDM4EPOLB | |
| SCHEMBL15300869 | 0.74 | PRKAB2 (0.43) | MEN1NPC1KMT2AKDM4EPOLB | |
| SCHEMBL4573426 | 0.66 | ALDH1A1 (0.42) | MEN1NPC1KMT2AKDM4ETDP1 | |
| SCHEMBL31014541 | 0.66 | — | — | |
| SCHEMBL16697716 | 0.65 | TUBB4A (0.41) | MEN1NPC1KMT2AKDM4EPOLB | |
| SCHEMBL19330958 | 0.64 | MEN1 (0.32) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL19869930 | 0.64 | PYCR1 (0.40) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL15301004 | 0.63 | SIGMAR1 (0.44) | KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |