SCHEMBL29134618

SCHEMBL29134618

O=C(c1ccc(Br)cc1)C(O)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
KDM4E B2RXH2 3/20 0.59
LMNA P02545 4/20 0.54
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.40
AKR1C3 P42330 1/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
RCE1 Q9Y256 1/20 0.38
HSP90AA1 P07900 1/20 0.38
NTSR1 P30989 1/20 0.38
CNR1 P21554 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20287780 0.92 ALDH1A1 (0.68) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL29173815 0.89 ALDH1A1 (0.73) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL29173813 0.89 LMNA (0.69) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL6202239 0.85 LMNA (0.74) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL6201840 0.85 LMNA (0.74) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL69238 0.83 CES2 (0.58) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL29247977 0.81 ALDH1A1 (0.71) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL30306610 0.79 ALDH1A1 (0.52) ALDH1A1KDM4ELMNACES2CES1
Benzoin SCHEMBL6199979 0.79 LMNA (0.64) ALDH1A1KDM4ELMNACES2CES1
SCHEMBL14525901 0.79 CES2 (0.53) ALDH1A1KDM4ELMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327079-A Covalent bond coupling-based long afterglow compound, system, preparation method and application 上海交通大学 2024-01-02 CN disclosed