Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201840 | 0.92 | LMNA (0.74) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL69238 | 0.90 | CES2 (0.58) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL6199979 | 0.89 | LMNA (0.64) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL5833429 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10665271 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL27696284 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL2025536 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL145 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL901258 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL28120851 | 0.86 | CES2 (1.00) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845533-B | Bis-4, 5-diaryl imidazole ring carbene gold complex, and preparation method and application thereof | 上海市第一人民医院 | 2023-09-29 | — | — | CN | disclosed |
| CN-113135958-B | Application of nitrogen heterocyclic carbene selenium-gold compound in preparation of carbapenem-resistant acinetobacter baumannii resistant medicine | 南京中医药大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-113135958-A | Application of nitrogen heterocyclic carbene selenium-gold compound in preparation of carbapenem-resistant acinetobacter baumannii resistant medicine | 南京中医药大学 | 2021-07-20 | — | — | CN | disclosed |
| EP-1425283-B1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
| US-6756432-B2 | POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-29 | — | — | US | disclosed |
| US-20030153655-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-14 | — | — | US | disclosed |
| US-6225132-B1 | DERIVATIZING AGENT COMPRISING A MULTIPHOTON-EMITTING RADIOISOTOPE AND A MOIETY THAT FORMS A NON-COVALENT CHEMICAL BOND WITH AN ANALYTE OF INTEREST, SUITABLE FOR DETECTION OF THE ANALYTE OF INTEREST | BIOTRACES, INC. | 2001-05-01 | — | — | US | disclosed |
| EP-0912899-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | Biotraces, Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5854084-A | Enhanced chromatography using multiphoton detection | BIOTRACES, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1998002750-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | BIOTRACES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| US-3937722-A | PHOTOSENSITIZERS, IRRADIATION POLYMERIZATION, CROSSLINKING | BAYER AG (DT) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | DPYD, TPMT, TYMP | LMNA 4528/4885CES2 2864/4885CES1 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.