Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17363249 | 0.86 | ACLY (0.54) | ACLYALDH1A1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL15220190 | 0.81 | IDH1 (0.47) | ACLYALDH1A1PTGS1PTGS2SLC22A12 | |
| SCHEMBL16887435 | 0.81 | MAPK1 (0.51) | ALDH1A1LMNAHPGDHSD17B10SMN1; SMN2 | |
| Lithium SCHEMBL31041218 | 0.81 | HPGD (0.68) | ACLYALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL20523634 | 0.80 | HSD17B10 (0.57) | ACLYALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL17374935 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL3234161 | 0.79 | LMNA (0.49) | ALDH1A1LMNAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL20523546 | 0.78 | NR3C1 (0.41) | ACLYALDH1A1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL26673643 | 0.78 | PTK2 (0.42) | ALDH1A1SMN1; SMN2PTGS1PTGS2MEN1 | |
| Hydrochloric Acid SCHEMBL9574614 | 0.78 | LMNA (0.47) | ALDH1A1LMNAHPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |