SCHEMBL15220190

SCHEMBL15220190

CS(=O)(=O)Nc1ccc(Br)cc1OC(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.47
ALPL P05186 6/20 0.46
ALDH1A1 P00352 1/20 0.45
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC22A12 Q96S37 1/20 0.43
CYP19A1 P11511 1/20 0.43
KIF11 P52732 1/20 0.43
WDR5 P61964 1/20 0.43
PGR P06401 1/20 0.40
HRH4 Q9H3N8 1/20 0.39
CCR9 P51686 1/20 0.39
ACLY P53396 1/20 0.39
CYP17A1 P05093 1/20 0.39
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16887440 0.83 MRGPRX1 (0.47) PTGS1PTGS2CYP19A1KIF11PGR
SCHEMBL29134896 0.81 ACLY (0.54) ALDH1A1PTGS1PTGS2SLC22A12CYP19A1
SCHEMBL20209032 0.78 NEU3 (0.51) ALPLALDH1A1KIF11CNR2
SCHEMBL5801365 0.78 PGR (0.50) PTGS1PTGS2SLC22A12CYP19A1KIF11
SCHEMBL3379317 0.78 KIF11 (0.65) PTGS2KIF11PGR
SCHEMBL30229910 0.78 PSEN1 (0.48) IDH1ALPLWDR5CCR9ACLY
SCHEMBL13011374 0.78 KIF11 (0.47) IDH1PTGS1PTGS2SLC22A12KIF11
SCHEMBL3376561 0.77 KIF11 (0.61) SLC22A12KIF11PGR
SCHEMBL2653076 0.76 ALPL (0.52) IDH1ALPLWDR5HRH4
SCHEMBL14880538 0.76 ALDH1A1 (0.48) ALDH1A1PTGS1PTGS2SLC22A12CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160313639-A1 PHOTOSENSITIVE RESIN COMPOSITION, PIXEL LAYER, PROTECTIVE FILM, SPACER, THIN-FILM TRANSISTOR, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY APPARATUS CHI MEI CORPORATION (TW) 2016-10-27 US disclosed
US-20150268554-A1 BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2015-09-24 US disclosed
US-9086532-B2 Blue photosensitive resin composition for color filter and uses thereof CHI MEI CORPORATION (TW) 2015-07-21 US disclosed
US-9081142-B2 Photosensitive resin composition for a color filter and uses thereof CHI MEI CORPORATION (TW) 2015-07-14 US disclosed
US-20150042931-A1 BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2015-02-12 US disclosed
US-20140346416-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2014-11-27 US disclosed
US-20130222738-A1 COLOR LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2013-08-29 US disclosed