Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135310 | 0.92 | SLC11A2 (0.42) | DRD4DRD3HRH3ROCK2ROCK1 | |
| SCHEMBL29135309 | 0.89 | HRH3 (0.55) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL29135319 | 0.85 | HRH3 (0.47) | HRH3 | |
| SCHEMBL29135318 | 0.84 | HRH3 (0.55) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL29135307 | 0.84 | HRH3 (0.52) | DRD3HRH3CYP11B1CYP11B2AKR1C3 | |
| SCHEMBL29135306 | 0.82 | HRH3 (0.47) | DRD4DRD3HRH3CYP11B2 | |
| SCHEMBL29135315 | 0.81 | HRH3 (0.40) | HRH3 | |
| SCHEMBL29135311 | 0.81 | DRD2 (0.44) | DRD4SLC6A3DRD3HRH3SLC6A2 | |
| SCHEMBL29135308 | 0.79 | HRH3 (0.43) | DRD4DRD3HRH3CYP11B1CYP11B2 | |
| SCHEMBL29135320 | 0.79 | HRH3 (0.44) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989085-B | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |