Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135316 | 0.83 | HRH3 (0.42) | HRH3PTPRCALOX5APFEN1MEN1 | |
| SCHEMBL29135318 | 0.83 | HRH3 (0.55) | HRH3PTPRCPTPN1CYP11B1CYP11B2 | |
| SCHEMBL29135310 | 0.81 | SLC11A2 (0.42) | HRH3DRD2DRD4DRD3GPR84 | |
| SCHEMBL29135319 | 0.80 | HRH3 (0.47) | HRH3MEN1KMT2A | |
| SCHEMBL29135312 | 0.79 | TMEM97 (0.41) | HRH3DRD4DRD3GPR84CYP11B1 | |
| SCHEMBL29135321 | 0.78 | HRH3 (0.44) | HRH3HIF1AALOX5APFEN1DHODH | |
| SCHEMBL29135320 | 0.78 | HRH3 (0.44) | HRH3PTPRCPTPN1ALOX5APFEN1 | |
| SCHEMBL28836300 | 0.76 | HRH3 (0.54) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL29135306 | 0.76 | HRH3 (0.47) | HRH3DRD2DRD4DRD3CYP11B2 | |
| SCHEMBL29135311 | 0.74 | DRD2 (0.44) | HRH3DRD2DRD4DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989085-B | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |