Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135312 | 0.89 | TMEM97 (0.41) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL29135316 | 0.86 | HRH3 (0.42) | HRH3THRB | |
| SCHEMBL29135307 | 0.85 | HRH3 (0.52) | HRH3CYP11B1CYP11B2DHODH | |
| SCHEMBL29135310 | 0.83 | SLC11A2 (0.42) | HRH3PRMT5WDR77 | |
| SCHEMBL29135319 | 0.83 | HRH3 (0.47) | HRH3 | |
| SCHEMBL29135318 | 0.82 | HRH3 (0.55) | HRH3CYP11B1CYP11B2 | |
| SCHEMBL29135321 | 0.81 | HRH3 (0.44) | HRH3PRMT5WDR77DHODH | |
| SCHEMBL29135306 | 0.80 | HRH3 (0.47) | HRH3CYP11B2PRMT5WDR77 | |
| SCHEMBL29135317 | 0.79 | DRD2 (0.44) | HRH3 | |
| SCHEMBL29135315 | 0.79 | HRH3 (0.40) | HRH3DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989085-B | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |