Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136213 | 0.84 | CCR2 (0.51) | LPOSIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL3091133 | 0.84 | P2RX4 (0.48) | SIGMAR1MAPTLMNATP53CMA1 | |
| SCHEMBL2117424 | 0.82 | HTR6 (0.48) | LPOSIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL694560 | 0.78 | TNF (0.44) | SIGMAR1KMT2ALMNAPOLBKDM4E | |
| SCHEMBL29136173 | 0.78 | ALDH1A1 (0.49) | KMT2ALMNAPOLBIDO1ALDH1A1 | |
| SCHEMBL30218812 | 0.75 | KMT2A (0.63) | LPOSIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL6087249 | 0.75 | KMT2A (0.63) | LPOSIGMAR1KMT2AMAPTLMNA | |
| SCHEMBL29136171 | 0.74 | SIGMAR1 (0.49) | LPOSIGMAR1KMT2ACMA1POLB | |
| SCHEMBL3086235 | 0.73 | TP53 (0.38) | KMT2ALMNATP53POLBKDM4E | |
| SCHEMBL3079071 | 0.73 | LMNA (0.50) | KMT2AMAPTLMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003739-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 安徽中医药大学 | 2023-11-07 | — | — | CN | disclosed |