Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4354003 | 0.89 | RPS6KB1 (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| Oxalic Acid SCHEMBL4354000 | 0.89 | RPS6KB1 (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL2911012 | 0.87 | NAPEPLD (0.41) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL2910280 | 0.84 | PDE10A (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL2908444 | 0.84 | PDE10A (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL90572 | 0.84 | PDE10A (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL27765904 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| Hydrochloric Acid SCHEMBL27510131 | 0.83 | GSK3B (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| Hydrochloric Acid SCHEMBL10626673 | 0.83 | GSK3B (0.45) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B | |
| SCHEMBL27765905 | 0.79 | NAPEPLD (0.42) | SLC6A2SLC6A4SLC6A3RPS6KB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038260-B1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | ORGANON NV (NL) | 2010-09-01 | — | — | EP | disclosed |
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2010-02-11 | — | — | US | disclosed |
| EP-2038260-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. Organon (NL) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007144409-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | THOP1, PRSS1, DPEP1 | SLC6A2 4580/4885SLC6A4 4243/4885SLC6A3 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.